Dr Karel Pacak

Dr. Karel Pacak is a board-certified endocrinologist as well as the current and tenured Chief of the Section on Medical Neuroendocrinology of the Eunice Kennedy Shriver NICHD at the National Institutes of Health (NIH) in Bethesda, MD. 

Dr. Pacak graduated summa cum laude from Charles University in Prague, Czech Republic where he received his MD, PhD and DSc degrees based on his scientific work done at the NIH. While at the NIH in 2000, he established internationally recognized, and patient-oriented pheochromocytoma/paraganglioma research program. Since then, he has devoted his scientific career to clinical and translational research in these tumors.

Recently, he has described the role of a new HIF2A gain-of-function somatic mutation in the pathogenesis of paraganglioma, somatostatinoma, and polycythemia known as the Pacak-Zhuang syndrome.

Together with Graeme Eisenhofer he co-established ISP, for which he served as the President and principal organizer of the first conference in 2005. 

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